Detalhe da pesquisa
1.
Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature
; 626(7997): 194-206, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096902
2.
Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding.
J Biol Chem
; 299(11): 105328, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37806493
3.
Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry.
Bioorg Med Chem
; 42: 116223, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34091303
4.
Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties.
J Biol Chem
; 290(26): 16330-42, 2015 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25953898
5.
Bispecific digoxigenin-binding antibodies for targeted payload delivery.
Proc Natl Acad Sci U S A
; 108(20): 8194-9, 2011 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21536919
6.
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.
Blood
; 118(2): 358-67, 2011 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21444918
7.
A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
ACS Chem Biol
; 17(9): 2595-2604, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36044633
8.
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.
Nucleic Acids Res
; 37(6): 2014-25, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19208642
9.
Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors.
ACS Med Chem Lett
; 12(9): 1435-1440, 2021 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34531952
10.
Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme.
J Med Chem
; 64(15): 11302-11329, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34292726
11.
Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors.
ACS Med Chem Lett
; 12(3): 389-396, 2021 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33738066
12.
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands.
Nat Commun
; 11(1): 6387, 2020 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318494
13.
Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors.
ACS Med Chem Lett
; 11(8): 1548-1554, 2020 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32832022
14.
A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Nat Commun
; 9(1): 1199, 2018 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29572442
15.
Discovery of a Potent, Orally Bioavailable PI4KIIIß Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo.
J Med Chem
; 61(15): 6705-6723, 2018 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29952567
16.
Structural biochemistry of ATP-driven dimerization and DNA-stimulated activation of SMC ATPases.
Curr Biol
; 14(19): 1778-82, 2004 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15458651
17.
Structural basis for transcription-coupled repair: the N terminus of Mfd resembles UvrB with degenerate ATPase motifs.
J Mol Biol
; 355(4): 675-83, 2006 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16309703
18.
Data for the crystal structure of APRIL-BAFF-BAFF heterotrimer.
Data Brief
; 6: 438-44, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26870754
19.
Crystal structure of human TWEAK in complex with the Fab fragment of a neutralizing antibody reveals insights into receptor binding.
PLoS One
; 8(5): e62697, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23667509
20.
Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties.
MAbs
; 5(1): 22-33, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23211638